First plant-made biologic approved

Biomedicines—Moving Biologic Agents into Approved Treatment Options

The development of biologic agents for therapeutic purposes, or biomedicines, has seen an active area of research both at the bench and in clinical trials. There is mounting evidence that biologic products can provide effective therapy for diseases that have been unresponsive to traditional pharmacologic approaches. Monoclonal antibody therapy for cancer and rheumatologic diseases has become a ...

Plant-Made Biologics

1 The Biodesign Institute, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA 2 School of Life Sciences, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA 3Department of Science and Technology for Agriculture, Forestry, Nature and Energy (DAFNE), University of Tuscia, Via San Camillo de Lellis snc, 01100 Viterbo, Italy 4Department of Biological Sys...

Evolution of Plant-Made Pharmaceuticals

The science and policy of pharmaceuticals produced and/or delivered by plants has evolved over the past twenty-one years from a backyard remedy to regulated, purified products. After seemingly frozen at Phase I human clinical trials with six orally delivered plant-made vaccines not progressing past this stage over seven years, plant-made pharmaceuticals have made a breakthrough with several pur...

AdeLE first prototype: experiences made

In this paper we describe first experiences with AdeLE prototype, a framework for adaptive e-learning utilising both eye tracking and content tracking technology. We outline features of the first prototype and their relevance for the user. We report more in detail about current research challenges where we observe users’ learning behaviour in real time by monitoring characteristics such as obje...

Plant-Made Pharmaceuticals: An Overview and Update